Ryan Seacrest talks about Simon Cowell to Conan O'Brien

Conan asked about Ryan’s relationship with Simon Cowell, saying “you guys fight like an old married couple” and observing that they “seem like spurned lovers at times!”

Ryan replied “he is an old man. He’s not like an older brother. It’s more like the weird cousin who tries to make out with a blood relative at Thanksgiving.”

Seriously, Ryan, your cousins sound way weirder than mine …

Ryan went on to talk about Simon’s lotions and potions, speculating “he’s admitted to having botox and if he didn’t have botox I think he would look like Angela Lansbury.”

Ryan talking about some of the more outstanding parts of Simon’s physique (click on the still to view the full video)

Click for Part 1: Ryan and Conan discuss Ryan’s tumultuous relationship with American Idol Judge Simon Cowell

Sometimes a contestant will walk out and you’ll think they have forgotten the lyrics because they’re nervous, and it’s just because they’re distracted by these nipples that are shooting at them!

We know that Ryan and Simon like to take shots at each other on air, and Ryan stated during the interview that he and Simon are good friends, but it’ll be fun to watch some of these comments as they make their way around the internet.